Circulating Tumor DNA (ctDNA) Cancer Risk Assessment Evolved

How cancer starts?

For a cancer to start, changes take place within the genes of a cell or a group of cells
It can take many years for a cell to divide and accumulate enough mutations to form a tumor
Cancer is the leading cause of death in Hong Kong and mainland China, and its incidence and mortality are increasing

Before the age of 75:

Almost 1 in 4 will attain cancer
Almost 1 in 12 will die cancer

Over 50% cancer cases are diagnosed at late-stages of the diseases

Over 34,000 people are diagnosed with cancer each year in Hong Kong
Over 50% of cancer cases are diagnosed late
Mirroring incidence trends, rates increased for cancers in younger individuals

「Cancer Prophet」Earlier Detection, Earlier Treatment

Lung cancer was the first leading cause of cancer deaths in Hong Kong
Over 80% lung cancer cases were diagnosed at advanced stages
The 5-year relative survival rates for early-stage cancers can be higher than 90%. For advanced-stage cancers, the rates drop to about 20%

Screening ctDNA is a better way for early cancer risk assessment

ctDNA is released from the tumor cell, which is dead or active, and then enters the blood.
As ctDNA comes from tumor cells, this is a significant biomarker for early cancer risk assessment.
For cancer risk assessment, we are screening the ctDNA, which has any gene mutations.

MYGENIA® Circulating Tumor DNA (ctDNA)
Cancer Risk Assessment Evolved - OEC


Interrogating 270 cancer-related genes in a single test
Comprehensively covering 38 and 42 common cancer-related diseases in males and females respectively
Unlike traditional hotspot-focused methods, the latest OEC detection technology interrogates all the coding regions of the target genes, providing unparalleled and comprehensive coverage of mutations in the 270 cancer-related genes (See the below photo)
OEC detection technology covers more gene mutations related to cancer pathogenesis

New Collect Sampling Method - More Convenient

Suitable For:

Unhealthy lifestyle: staying up late and sleep deprivation
Overweight, lack of exercise
Smoking, drinking alcohol and other unhealthy diet
Staying in highly polluted or radiologically contaminated places
Persons with non-communicable diseases or immunocompromised conditions
Persons with family history of cancer

Test Specifications

Test Code Methodology Specimen Requirements Turnaround Time
OEC NGS (Next Generation Sequencing) 20ml cfDNA Blood Tube (PAXgene) 30 Working Days