Earlier Screening and Earlier Prevention for Better Health Management
Breast and Gynecologic Cancers are the leading killers of Hong Kong women. According to the Hong Kong Cancer Registry, there were more than 7,200 new cases for the following women’s cancers in 2019, accounting for over 40% of all new cancer cases1#.
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If you have inherited a mutation in one of the cancer-related genes, your risk of developing cancer is greatly increased
Inherited genetic mutations play a more significant role in the following gynecologic cancers
| Breast | |
| Ovary | |
| Corpus uteri |
Taking breast cancer as an example, a study published in Hong Kong Medical Journal summarized that individuals with an inherited mutation in one of the genes listed below have a significantly increased lifetime risk of breast cancer2.
Is cancer usually inherited?
The medical community recognized that there are two hereditary forms of cancer
Familial Cancer
| More than one family members who have the same or a related cancer | |
| May due to the interactions between certain genes and environmental factors | |
| About 15% cancer cases are familial |
Hereditary Cancer
| Higher risk of developing certain types of cancer due to inherited mutations in certain genes | |
| The gene mutations may be passe on to succeeding generations | |
| About 10% of all cancers are hereditary 3 | |
| To date, more than 80 Genes are known to be associated with Hereditary Cancers 4 |
PanHERED™ Hereditary Breast and Gynecologic Cancers Panel
| Allows the comprehensive analysis of genes associated with the above-mentioned hereditary breast and gynecologic cancers | |
| Provides results that may help guide subsequent surveillance and possible preventive measures |
Test Specifications
| Test Code | Methodology | Specimen Requirements | Turnaround Time |
|---|---|---|---|
| HBG | NGS (Next Generation Sequencing) | 6ml blood in Lavender-top EDTA tube | 4-6 Weeks |
Reference
- 1 香港防癌會網站, 最新癌症統計
- 2 Hong Kong Medical Journal. A new paradigm of genetic testing for hereditary breast/ovarian cancers
- 3 The Genetics of Cancer. National Cancer Institute. U.S. Department of Health and Human Services
- 4 遺傳性癌症 - 台大醫院基因醫學部
- ^ National Comprehensive Cancer Network