Prostate Cancer Screeing Test (BRCA1+2 & PSA)

Men should be more aware of prostate health. The earlier it is discovered, the greater the chance of successful treatment and effective control of the condition.

In the past two decades, prostate cancer has reached its highest incident rate and ranked the men's 4th most lethal cancer in Hong Kong, One in every 26 men is at risk for prostate cancer in their lifetime. In 2018 alone, more than one million new cases was were reported globally.

What is Prostate cancer and its causes ?

The prostate is the male's sex gland. It is responsible for the production of protective and nourishing fluids for the sperms to form semen. Prostate cancer is caused by the abnormal growth of prostate cells.
 
The cause of prostate cancer is still unknown. But we already know some of the pontential factors that will increase the risk of developing a prostate cancer.

The main risk factors for prostate cancer include:

Age, ethnicity, degree of exercising/physical activity, eating habits, family history and genetic mutations

Common symptoms of prostate cancer

Prostate cancer does not show any symptoms at an early stage, and many patients do not even notice it. Common symptoms in patients with symptoms include :
 
  • Difficulty in urinating or poor urinary flow
  • Hematuria
  • Pain at the lower back, pelvis and hips

What is PSA Test ?

The PSA test is a blood test that measures the amount of prostate specific antigen (PSA) in your blood. PSA is a protein produced by normal cells in the prostate and also by prostate cancer cells. It’s normal to have a small amount of PSA in your blood, and the amount rises slightly as you get older and your prostate gets bigger. A raised PSA level may suggest you have a problem with your prostate.

Test Specifications

Test Code
Methodology
Specimen Requirements
Turnaround Time
OPB
Next generation sequencing (NGS)
6ml EDTA blood + 4ml Clot-blood
within 4 weeks

What is BRCA Exome Sequencing ?

Next-generation sequencing (NGS)-based BRCA1+2 exome sequencing provides comprehensive coverage of all coding areas of the genes

Frequently asked questions (FAQs)

Q: Who should order this test ?
A: Based on the emerging scientific evidence obtained in the IMPACT study, The Institute of Cancer Research (UK) encourages men over 40 with BRCA2 mutated gene should get regular PSA screening. All men, especially those at higher risk, should have their BRCA genes sequenced to identify prostate cancer risk as early as possible.
 
Q: How often ?
A: Men are recommended to have the PSA test once every 3 years; for high-risk individuals, they are recommended to have the test once per year.
 
Q: Are there any advanced tests to diagnose prostate cancer ?
A: Because the PSA blood test is not a diagnostic test, if the test results are abnormal, the doctor may refer you to a specialist for further tests, including regular PSA blood tests, prostate ultrasounds and biopsies (sampling prostate tissue samples), to diagnose if you have prostate cancer.
 
Q: What are the treatments for prostate cancer ?
A: If you have been diagnosed with prostate cancer, the doctor will decide the most suitable treatment method depending on the individual's condition, including the size of the tumor, whether the cancer cells have spread, and whether there are other diseases.

How to get started

Our tests must be ordered by a doctor. Ask your doctor if a Mygenia test is right for you. We can help you find a doctor if you don’t have one.

I have a doctor
References
  1. Hong Kong Cancer Registry, Hospital Authority
  2. Department of Health