EGFR mutation screening

What is EGFR?

Epidermal growth factor receptor (EGFR) is a protein found on the surface of cells. It helps cells grow and divide. It is usually the primary target in targeted therapies.

How doesEGFR mutation cause lung cancer?

Some non-small cell lung cancer (NSCLC) cells have too many EGFRs, which causes them to grow faster and uncontrollably. Mutations in the EGFR are present in 10% to about 25% of NSCLC tumors.

Why is detecting EGFR important?

EGFR-targeted therapy is the first-most used approach in treatment of multiple cancers including NSCLC. Mutated-EGFRs have chance of causing drug resistance. Thus, the detection of the mutation can help diagnosis, prognosis, treatment, and predicting patient outcome in response to targeted therapy for multiple cancer types.

Who should consider this test?

Patients who are suffering from cancers including NSCLC; or patients who have received targeted therapy and failed to show signs of recovery are both advised to perform this test.

Test Specifications

Test Code
Specimen Requirements
Turnaround Time
Sanger sequencing
4 FFPE unstained sections (6 μm) with at least 20% of tumor content
5 days

What should I do if my test results are positive?

Please consult your physicians for professional advices.

How to get started

Our tests must be ordered by a doctor. Ask your doctor if a Mygenia test is right for you. We can help you find a doctor if you don’t have one.

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