What is EGFR？
Epidermal growth factor receptor (EGFR) is a protein found on the surface of cells. It helps cells grow and divide. It is usually the primary target in targeted therapies.
How doesEGFR mutation cause lung cancer?
Some non-small cell lung cancer (NSCLC) cells have too many EGFRs, which causes them to grow faster and uncontrollably. Mutations in the EGFR are present in 10% to about 25% of NSCLC tumors.
Why is detecting EGFR important?
EGFR-targeted therapy is the first-most used approach in treatment of multiple cancers including NSCLC. Mutated-EGFRs have chance of causing drug resistance. Thus, the detection of the mutation can help diagnosis, prognosis, treatment, and predicting patient outcome in response to targeted therapy for multiple cancer types.
Who should consider this test?
Patients who are suffering from cancers including NSCLC; or patients who have received targeted therapy and failed to show signs of recovery are both advised to perform this test.
What should I do if my test results are positive?
Please consult your physicians for professional advices.