What does “pan-heme” stand for?
“Pan” means “all” and “heme” means “blood”. Cquence pan-heme panel literally means the detection of all the genes related to blood malignancies. Leukemia, lymphoma and myeloma are some of the examples of blood malignancies. There are around 1000 cases each year of blood malignancies diagnosed in Hong Kong.
How does this test help treat cancer?
This test enables doctors in determining the best medication for blood malignancies patients. Cquence pan-heme panel is a precision medical test designed to determine 73 genes that contribute to the cancer activity and resistance against treatment in blood malignancies (eg. JAK2). Finding out these cancer genes is important in making decisions and predicting responses for targeted-therapies and/or other treatments specific for the patient tested.
What are these genes in the panel and how are they related to blood malignancies?
The major difference which separates a cancer cell from a normal cell is its uncontrolled cell growth with an exceptionally higher survival rate. These “enhanced” abilities are contributed by changes in the genetic information, or genes, of these cancer cells. Some of these changes, like JAK2, lead to uncontrolled cell growth of abnormal blood cells.
Who should consider this test?
Patients who are suffering from a spectrum of blood malignancies; or patients who have received therapy and failed to show signs of recovery; both are advised to perform this test.
What should I do if my test results are positive?
Please consult your physicians for professional advices.