What is the test for?
Cquence GIST genotyping panel provides hopes for recovery and improves quality of life for patients with gastro-intestinal stromal tumors (GIST). GIST refers to tumor cells found in the digestive system, most commonly the stomach (gastro) and the intestines (intestinal). “Stromal” means that these tumors develop from the connective tissues that support and control the movement of the gut.
How does this test help treat GIST?
This test enables doctors in determining the best medication for gastro-intestinal stromal tumors (GIST). Cquence GIST genotyping panel is a precision medical test designed to determine and categorize (genotyping) 23 genes related to GIST. Finding out these cancer genes is important in making decisions and predicting responses for targeted-therapies and/or other treatments specific for the patient tested.
What are cancer genes and how are they related to GIST?
The major difference which separates a cancer cell from a normal cell is its uncontrolled cell growth with an exceptionally higher survival rate. These “enhanced” abilities are contributed by changes in the genetic information, or genes, of these cancer cells. Some of these changes, like C-KIT, lead to uncontrolled growth of gastral and intestinal cells.
Who should consider this test?
Patients with GIST and/or patients who have received targeted therapy and failed to show signs of recovery are advised to perform this test.
How are samples obtained?
“Biopsy” is the surgical process which the doctor collects a section of suspected cancer tissue and sends it to the laboratory for analysis.
What should I do if my test results are positive?
Please consult your physicians for professional advices.